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Sarah M. London

Sarah M. London serves as Chief Executive Officer of Centene Corporation, a Fortune 25 company and the nation's leading healthcare payer focused on government-sponsored programs. Appointed CEO in March 2022, she became the youngest female CEO of a Fortune 500 company, replacing Michael Neidorff. Centene focuses on government-sponsored healthcare programs and serves under-insured and uninsured individuals, managing coverage for millions of Americans across Medicaid, Medicare, and Marketplace plans.

London spent her career at the intersection of health data, technology and healthcare delivery transformation. Before becoming CEO, she served as Vice Chairman of Centene, overseeing strategy, technology, ancillary services, enterprise compliance and quality. Under her leadership, Centene sharpened its focus on three core businesses – Medicaid, Medicare, and Marketplace – while investing in integrated care for dual-eligible populations and Individual Coverage Health Reimbursement Arrangements (ICHRA).

Career History

  • Chief Executive Officer, Centene Corporation (2022–present)
  • Vice Chairman, Centene Corporation (2021–2022)
  • Senior Vice President of Technology Innovation and Modernization, Centene Corporation (2020–2021)
  • Operating Partner, Optum Ventures, venture capital arm of UnitedHealth Group
  • Chief Product Officer, Optum Analytics
  • Vice President of Client Services, Optum Analytics
  • Client Services and Operations Lead, Humedica (clinical analytics start-up, acquired by Optum)
  • Positions at Accretive Health (now R1 RCM)
  • Positions at Health Leads, national organization addressing social determinants of health

London graduated magna cum laude from Harvard College where she played Division I tennis. She holds a Master of Business Administration degree with High Honors from the University of Chicago Booth School of Business. After her Harvard degree in history and literature, London spent two years in the film industry before transitioning to healthcare, first at Harvard supporting health and education initiatives, then at nonprofit Health Leads.

London has been included on Forbes "Power Women" list and Fortune's "Most Powerful Women" list for three consecutive years, and was awarded Modern Healthcare's "Leading Women Vanguard Award" in 2025. Under her leadership, Centene has been recognized by Fortune as one of the "World's Most Admired Companies" and one of "America's Most Innovative Companies," and by Newsweek as one of "America's Greatest Workplaces" for three consecutive years. Colleagues note London's distinctive ability to connect complex healthcare situations with strategic clarity and deep care for stakeholder impact.

What Sarah London could bring to her role as CEO at Centene: London's background combining healthcare data analytics, technology modernization, and deep experience across government-sponsored programs, from small nonprofits to Fortune 500 scale, positions her to drive Centene's transformation toward integrated, value-based care while navigating evolving federal policy constraints. Her track record of building cross-functional teams, redirecting resources toward community impact, and applying systems-thinking to healthcare delivery suggests she is uniquely equipped to advance Centene's mission of providing accessible care to underserved populations amid significant regulatory change.

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